Note: Most of these characters have to be unlocked. Only Mimi, Nyami, The King, and Mary are available from the get-go.
- A remake of Konami's long-running Taisen Puzzle-dama series of puzzle games, which in themselves are a rip-off of Compile's Puyo Puyo series, where you clear four blobs of the same color to eliminate them off the field. The key difference in Taisen Puzzle-dama is that you only need to have three of something of the same color to clear them off the board. Traditionally in Taisen Puzzle-dama they're smiling circles, but in this case they're replaced by Pop-kuns.
- This is the only PS2 Pop'n Music game that doesn't feature traditional button-hitting gameplay. It was also the only one until pop'n music (Wii) that required you to go online to access download content.
- Suwa Hideo and Sanae Shintani's voices are heard in game.